PAGB response to antihistamines and impaired male fertility

Published on: 8 March 2018


John Smith, PAGB Chief Executive, comments:

“We welcome any new research* on over-the-counter (OTC) medicines, but this report focuses exclusively on previous and known studies of the effects of antihistamines on animals. The researchers’ key conclusion is that further human clinical studies are needed before any clear links between antihistamines and male fertility can be established.

“People taking OTC antihistamines should not be concerned by this research. Antihistamines are an effective and appropriately safe way to provide relief from symptoms of allergies if used in accordance with the clear on-pack instructions and the patient information leaflet inside. Anyone who has any concerns about taking a medicine should speak to a pharmacist for advice. Pharmacists are highly trained healthcare professionals and can provide useful information and guidance on OTC medicines.”

*A study carried out by researchers at the Instituto de Biologia y Medicines Experimental (YBIME-CONICET) and published in the journal Reproduction has suggested that the use of antihistamines could be linked to impaired fertility in men. 

PAGB response to antihistamines and impaired male fertility